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Tyrosinase-IN-11

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Chemical Structure| 240797-64-2 同义名 : -
CAS号 : 240797-64-2
货号 : A2021652
分子式 : C15H14O5
纯度 : 98%+
分子量 : 274.269
MDL号 : N/A
存储条件：

粉末 Keep in dark place,Inert atmosphere,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Tyrosinase-IN-11 exhibits potent inhibition against tyrosinase, with IC50 values of 50 nM and 64 nM for L-tyrosinase and L-dopa, respectively. It demonstrates significant antioxidant activity and low cytotoxicity, rendering it valuable for skin hyperpigmentation research[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.65mL

0.73mL

0.36mL

18.23mL

3.65mL

1.82mL

36.46mL

7.29mL

3.65mL
参考文献

[1]Songtao Xue, et al. Design, Synthesis, and Biological Evaluation of Novel Hybrids Containing Dihydrochalcone as Tyrosinase Inhibitors to Treat Skin Hyperpigmentation. J Med Chem. 2023 Apr 13;66(7):5099-5117.

[2]Wang Y, et al. Discovery of bardoxolone derivatives as novel orally active necroptosis inhibitors. Eur J Med Chem. 2021 Feb 15;212:113030.