产品说明书
TAS-301
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同义名 : | - |
| CAS号 : | 193620-69-8 | |
| 货号 : | A200976 | |
| 分子式 : | C23H19NO3 | |
| 纯度 : | 99%+ | |
| 分子量 : | 357.4 | |
| MDL号 : | MFCD05865245 | |
| 存储条件： |
粉末 Sealed in dry,Room Temperature 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 40 mg/mL(111.92 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | TAS-301 inhibits PKC activation and Ca2+ influx in a concentration-dependent manner, induced by PDGF, achieving 62.7% inhibition at 10 μM. It also reduces PMA-induced AP-1 activity, with 38% and 67.6% inhibition at concentrations of 3 and 10 μM, respectively[1]. Dose-dependently, TAS-301 (0.3-3 μM) curtails cell migration induced by various growth factors (PDGF-BB, IGF-1, HB-EGF) and diminishes bFGF-induced BrdU incorporation, particularly at 3 and 10 μM[2]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
2.80mL 0.56mL 0.28mL |
13.99mL 2.80mL 1.40mL |
27.98mL 5.60mL 2.80mL |
| 参考文献 |
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