产品说明书

ML381

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Chemical Structure| 1623481-80-0 同义名 : VU0488130
CAS号 : 1623481-80-0
货号 : A1955025
分子式 : C21H21N3O4
纯度 : 98%+
分子量 : 379.409
MDL号 : MFCD34597614
存储条件：

粉末 Sealed in dry,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(276.75 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 ML381, also known as VU0488130, is a highly selective, CNS-penetrant orthosteric antagonist of the mAChR M5 (IC50 = 450 nM; Ki = 340 nM). ML381 exhibits instability in rat plasma and is primarily used as a molecular probe for in vitro and electrophysiological studies[1][2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.64mL

0.53mL

0.26mL

13.18mL

2.64mL

1.32mL

26.36mL

5.27mL

2.64mL