Benzyl alcohol

产品说明书

Print
Chemical Structure| 100-51-6 同义名 : 苯甲醇 ;Benzenemethanol
CAS号 : 100-51-6
货号 : A194236
分子式 : C7H8O
纯度 : 98%
分子量 : 108.138
MDL号 : MFCD00004599
存储条件:

Pure form Keep in dark place,Inert atmosphere,Room temperature

In solvent -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 1.5 mg/mL(13.87 mM),注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

H2O: 20 mg/mL(184.95 mM),配合低频超声助溶

无水乙醇: 100 mg/mL(924.75 mM),注意:无水乙醇开封后,易挥发,也会吸收空气中的水分,导致溶解能力下降,请避免使用开封较久的乙醇

动物实验配方:
生物活性
描述 Benzyl alcohol is an aromatic alcohol with a mild aromatic odor and acts as an inhibitor of the P450 enzyme. It modulates the Toll-Like Receptor 4, thereby reducing the inflammatory response associated with liver injury in mice[1].[2].[3].
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT00795678 - Completed - United States, New York ... 展开 >> Memorial Sloan Kettering New York, New York, United States, 10065 United States, Ohio Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center Cleveland, Ohio, United States, 44195 收起 <<
NCT00787761 Myeloproliferative Disorders ... 展开 >> Kidney Cancer Leukemia Lymphoma Multiple Myeloma and Plasma Cell Neoplasm Myelodysplastic Syndromes Myelodysplastic/Myeloproliferative Diseases 收起 << Phase 2 Completed - United States, Georgia ... 展开 >> Blood and Marrow Transplant Group of Georgia Atlanta, Georgia, United States, 30342 收起 <<
NCT02340962 Hepatitis C, Chronic Phase 2 Completed - Taiwan ... 展开 >> Kaohsiung Medical University Chung-Ho Memorial Hospital Kaohsiung, Taiwan 收起 <<
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

9.25mL

1.85mL

0.92mL

46.24mL

9.25mL

4.62mL

92.47mL

18.49mL

9.25mL

参考文献

[1]Friedlander G, et al. Benzyl alcohol increases membrane fluidity and modulates cyclic AMP synthesis in intact renal epithelial cells. Biochim Biophys Acta. 1987 Oct 2;903(2):341-8.

[2]Du K, et al. Benzyl alcohol protects against acetaminophen hepatotoxicity by inhibiting cytochrome P450 enzymes but causes mitochondrial dysfunction and cell death at higher doses. Food Chem Toxicol. 2015 Dec;86:253-61.

[3]Cai C, et al. Benzyl alcohol attenuates acetaminophen-induced acute liver injury in a Toll-like receptor-4-dependent pattern in mice. Hepatology. 2014 Sep;60(3):990-1002.