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PARP10-IN-3

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Chemical Structure| 2225800-19-9 同义名 : -
CAS号 : 2225800-19-9
货号 : A1937108
分子式 : C14H12N2O3
纯度 : 99%+
分子量 : 256.257
MDL号 : N/A
存储条件：

粉末 Sealed in dry,Room Temperature

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 50 mg/mL(195.12 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 PARP10-IN-3 is a specific mono-ADP-ribosyltransferase PARP10 inhibitor, with an IC50 of 480 nM for human PARP10. Additionally, PARP10-IN-3 demonstrates significant inhibition of PARP2 and PARP15, with IC50 values of 1.7 μM for human PARP2 and human PARP15, respectively [1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.90mL

0.78mL

0.39mL

19.51mL

3.90mL

1.95mL

39.02mL

7.80mL

3.90mL
参考文献

[1]Patricia Korn, et al. Evaluation of 3- and 4-Phenoxybenzamides as Selective Inhibitors of the Mono-ADP-Ribosyltransferase PARP10. ChemistryOpen. 2021 Oct;10(10):939-948.