生物活性 | |||
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描述 | Propargyl-PEG3-acid is a non-cleavable linker for ADCs, consisting of a 3-unit PEG chain. It also serves as a PEG-based linker for PROTACs synthesis, enabling the formation of 6-OHDA-PEG3-yne, which includes 6-OHDA and Propargyl-PEG3-acid [1]. Propargyl-PEG3-acid serves as a click chemistry reagent, featuring an alkyne group capable of participating in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions with molecules containing azide groups. |
实验方案 | |||
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1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
4.62mL 0.92mL 0.46mL |
23.12mL 4.62mL 2.31mL |
46.25mL 9.25mL 4.62mL |
参考文献 |
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