产品说明书

L-Chicoric Acid

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Chemical Structure| 70831-56-0 同义名 : 菊苣酸 ;(-)-Chicoric acid;trans-Caffeoyltartaric acid;NSC 99173;Dicaffeoyltartaric acid;Chicoric acid
CAS号 : 70831-56-0
货号 : A176803
分子式 : C22H18O12
纯度 : 99%+
分子量 : 474.371
MDL号 : MFCD22683653
存储条件：

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(221.35 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 L-Chicoric acid, a natural product isolated and purified from the herbs of Echinacea purpurea, is an inhibitor of human immunodeficiency virus type 1 (HIV-1) integrase in vitro and of HIV-1 replication in tissue culture.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.11mL

0.42mL

0.21mL

10.54mL

2.11mL

1.05mL

21.08mL

4.22mL

2.11mL
参考文献

[1]Landmann M, Kanuri G, et al. Oral intake of chicoric acid reduces acute alcohol-induced hepatic steatosis in mice. Nutrition. 2014 Jul-Aug;30(7-8):882-9.

[2]Ryan A Reinke. l-Chicoric acid inhibits human immunodeficiency virus type 1 integration in vivo and is a noncompetitive but reversible inhibitor of HIV-1 integrase in vitro. Virology Volume 326, Issue 2, 1 September 2004, Pages 203–219