产品说明书
Ginsenoside Rh1
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同义名 : | Prosapogenin A2;Sanchinoside Rh1;CS-3834;HY-N0604;20(S)-Ginsenoside Rh1;Sanchinoside B2 |
| CAS号 : | 63223-86-9 | |
| 货号 : | A176502 | |
| 分子式 : | C36H62O9 | |
| 纯度 : | 98% | |
| 分子量 : | 638.872 | |
| MDL号 : | MFCD09951797 | |
| 存储条件： |
粉末 Sealed in dry,2-8°C 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 105 mg/mL(164.35 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Ginsenoside Rh1, a protopanaxatriol type ginsenoside. Ginsenoside Rh1 exhibits potent biological activities such as antistress, anti-oxidant, anti-inflammatory and immunomodulatory effects. Ginsenoside Rh1 might be useful in the treatment of sepsis by targeting HMGB1(High mobility group box 1) [3]. Ginsenoside Rh1 decreased the expressions of peroxisome proliferator-activated receptor (PPAR)-γ, CCAAT/enhancer-binding protein (C/EBP)-α, fatty acid synthase, and adipocyte fatty acid-binding protein. Oral administration of ginsenoside Rh1 (20 mg/kg) suppressed body and epididymal fat weight gains and plasma triglyceride level in DIO (high fat diet-induced obesity) mice[4]. Ginsenoside Rh1 was not toxic to CRC cells at various concentrations (0, 50 or 100 µM) and treatment durations (24 or 48 h). However, cell proliferation was suppressed by Rh1 in a dose-dependent manner. Rh1 (100 µM) significantly inhibited cell migration and invasion in vitro[5]. Ginsenoside Rh1 is able to upregulate glucocorticoid receptor (GR) level, suggesting Rh1 may improve glucocorticoid efficacy in hormone-dependent diseases[6]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
1.57mL 0.31mL 0.16mL |
7.83mL 1.57mL 0.78mL |
15.65mL 3.13mL 1.57mL |
| 参考文献 |
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