产品说明书
Streptomycin sulfate
 |
同义名 : | Streptomycin (sulfate);Phytomycin |
| CAS号 : | 3810-74-0 | |
| 货号 : | A172127 | |
| 分子式 : | C42H84N14O36S3 | |
| 纯度 : | ≥720I.U./mg | |
| 分子量 : | 1457.38 | |
| MDL号 : | - | |
| 存储条件： |
粉末 Keep in dark place,Inert atmosphere,2-8°C 液体 -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : |
H2O: 100 mg/mL(68.62 mM) |
|
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Streptomycin sulfate is an aminoglycoside antibiotic that inhibits protein synthesis. Most patients with bilateral Meniere's disease treated with streptomycin sulfate titration therapy and followed over the long term have either improvement or relief of their disabling vertigo[3]. Animal experiments have demonstrated severe damage to the vestibular hair cells after streptomycin treatment. The morphologic changes indicated that streptomycin damaged the cytoplasmic granules and the plasma membrane infoldings of the dark cells[4]. A case of community-acquired endocarditis caused by Enterococcus (Streptococcus) faecalis with high-level resistance to gentamicin sulfate but not to streptomycin sulfate is described[5]. | ||
| 临床研究 | |||||
|---|---|---|---|---|---|
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
| NCT01432925 | Mycobacterium Ulcerans Disease... 展开 >> Buruli Ulcer 收起 << | Not Applicable | Unknown | - | Benin ... 展开 >> Buruli ulcer center Allada Allada, Benin Buruli ulcer center Lalo Lalo, Benin 收起 << |
| NCT00023374 | Tuberculosis | Not Applicable | Completed | - | - |
| NCT00495326 | Tuberculosis ... 展开 >>Aids Hiv Infections 收起 << | Phase 2 Phase 3 | Completed | - | Mozambique ... 展开 >> Health centre of Alto Mae, Chamanculo district Maputo, Mozambique Health centre of Josue Macao Maputo, Mozambique Health centre of Malavane Maputo, Mozambique 收起 << |
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
0.69mL 0.14mL 0.07mL |
3.43mL 0.69mL 0.34mL |
6.86mL 1.37mL 0.69mL |
| 参考文献 |
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