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6-Maleimidohexanoic acid N-hydroxysuccinimide ester

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Chemical Structure| 55750-63-5 同义名 : 6-(马来酰亚胺基)己酸琥珀酰亚胺酯 ;EMCS
CAS号 : 55750-63-5
货号 : A167523
分子式 : C14H16N2O6
纯度 : 98%
分子量 : 308.287
MDL号 : MFCD00043043
存储条件:

粉末 Inert atmosphere,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 200 mg/mL(648.75 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:

IP 2% DMSO+2% Tween80+30% PEG300+water 10 mg/mL clear

PO 0.5% CMC-Na 61 mg/mL suspension

生物活性
描述 6-Maleimidohexanoic acid N-hydroxysuccinimide ester (EMCS) is a heterobifunctional cross-linking reagent. It is widely used for the preparation of hapten conjugate and enzyme immunoconjugates, demonstrating its utility in biomedical research and diagnostic applications[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.24mL

0.65mL

0.32mL

16.22mL

3.24mL

1.62mL

32.44mL

6.49mL

3.24mL

参考文献

[1]Shinya Kida, et al. Studies on heterobifunctional cross-linking reagents, 6-maleimidohexanoic acid active esters. Chem Pharm Bull (Tokyo). 2007 Apr;55(4):685-7.