产品说明书

Norfloxacin

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Chemical Structure| 70458-96-7 同义名 : 氟哌酸 ;MK-0366
CAS号 : 70458-96-7
货号 : A165613
分子式 : C16H18FN3O3
纯度 : 98+%
分子量 : 319.331
MDL号 : MFCD00079532
存储条件:

粉末 Keep in dark place,Sealed in dry,Room Temperature

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 4 mg/mL(12.53 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 Norfloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria, which functions by inhibiting DNA gyrase.
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT01508507 - Unknown March 2014 India ... 展开 >> Regional Medical Research Center Recruiting Chandrashekharpur, Bhubaneswar, Odisha, India, 751016 Contact: Shantanu K Kar, MD    91-674-301322    rmrcdir@sancharnet.in    Contact: Anna S Kerketta, MBBS    91-674-2301387    solani_bara@rediffmail.com    Sub-Investigator: Hemant K Khuntia, MBBS 收起 <<
NCT02099240 Osteomyelitis Early Phase 1 Recruiting September 2019 United States, Kentucky ... 展开 >> University of Louisville Recruiting Louisville, Kentucky, United States, 40202 Contact: Julio A Ramirez, MD    502-852-1148    jarami01@louisville.edu    Contact: David Seligson, MD    502-852-0923    d0seli01@louisville.edu    Sub-Investigator: Forest Arnold, DO          Sub-Investigator: Timothy Wiemkwn, PhD          Sub-Investigator: Robert Kelley, PhD          Sub-Investigator: James Summersgill, PhD          Sub-Investigator: Ruth Carrico, PhD          Sub-Investigator: Julie Harting, PharmD          Sub-Investigator: Paula Peyrani, MD          Principal Investigator: David Seligson, MD          Sub-Investigator: Craig Roberts, MD          Principal Investigator: Julio Ramirez, MD 收起 <<
NCT00701792 Cirrhosis Not Applicable Completed - France ... 展开 >> service d'hépatologie CHU jean Minjoz Besancon, France, 25000 CHRU CAEN - Service d'hépato-gastroentérologie Caen, France, 14033 Hôpital Beaujon - Hépato-gastroentérologie Clichy, France, 92110 CHU Henri Mondor - Hépato-gastroentérologie Creteil, France, 94010 Hépato-gastroenterologie CHU Bocage Dijon, France, 21034 Centre d'épidémiologie de population EPI 106 Dijon, France, 21079 Hôpital Bon secours - Hépato-gastroentérologie Metz, France, 57000 Hôpital Saint-Eloi - Hépato-gastroentérologie Montpellier, France, 34295 Hôpital Pitié-Salpétrière - Hépato-gastroentérologie Paris, France, 75013 Hepato-gastroenterologie Poitiers, France, 86021 CHU Reims - hépato-gestroentérologie Reims, France, 51092 Clinique des maladies du foie Hôpital Pontchailloux Rennes, France, 35000 Hôpital Purpan - Hépato-gastroentérologie Toulouse, France, 31059 收起 <<
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.13mL

0.63mL

0.31mL

15.66mL

3.13mL

1.57mL

31.32mL

6.26mL

3.13mL

参考文献

[1]Dong J, Ruan J, et al. In vitro synergistic effects of fisetin and norfloxacin against aquatic isolates of Serratia marcescens. FEMS Microbiol Lett. 2016 Jan;363(1):fnv220.

[2]Gadebusch HH, Shungu DL, et al. Comparison of the antibacterial activity of norfloxacin (MK 0366, AM 715), a new organic acid, with that of other orally absorbed chemotherapeutic agents. Infection. 1982 Jan;10(1):41-4.