Anticancer agent 43

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Chemical Structure| 2470015-35-9 同义名 : -
CAS号 : 2470015-35-9
货号 : A1603722
分子式 : C14H9FN2O3S2
纯度 : 98%+
分子量 : 336.361
MDL号 : N/A
存储条件：

Pure form Inert atmosphere,2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 120 mg/mL(356.76 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Anticancer Agent 43 is an effective anticancer compound. It promotes apoptosis through mechanisms dependent on caspase 3, PARP1, and Bax. Additionally, Anticancer Agent 43 causes DNA damage[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.97mL

0.59mL

0.30mL

14.86mL

2.97mL

1.49mL

29.73mL

5.95mL

2.97mL
参考文献

[1]Kryshchyshyn-Dylevych A, et al. Synthesis of novel indole-thiazolidinone hybrid structures as promising scaffold with anticancer potential. Bioorg Med Chem. 2021; 50:116453.