产品说明书
Ethoxyquin
 |
同义名 : | 乙氧基喹啉 ;NSC 6795;Santoquin;HSDB 400;EMQ;Amea 100;Quinol;Santoflex |
| CAS号 : | 91-53-2 | |
| 货号 : | A156299 | |
| 分子式 : | C14H19NO | |
| 纯度 : | 90% (GC) | |
| 分子量 : | 217.307 | |
| MDL号 : | MFCD00023883 | |
| 存储条件： |
粉末 Sealed in dry,Room Temperature 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 50 mg/mL(230.09 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Ethoxyquin (EQ) does not inhibit Paclitaxel's (PTX) ability to induce cell death in four different breast cancer cell lines. Importantly, the neuroprotective effect of Ethoxyquin is only observable when Hsp90 levels are not reduced; a decrease in Hsp90 abrogates this neuroprotection[2]. Ethoxyquin is most effective as a neuroprotectant at concentrations ranging from 30 to 300 nM. Higher concentrations in the micromolar (μM) range fail to enhance neuroprotection and, in fact, result in the loss of these neuroprotective properties[3]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
4.60mL 0.92mL 0.46mL |
23.01mL 4.60mL 2.30mL |
46.02mL 9.20mL 4.60mL |
| 参考文献 |
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