产品说明书

STING-IN-3

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Chemical Structure| 2244881-69-2 同义名 : C-171
CAS号 : 2244881-69-2
货号 : A1549680
分子式 : C17H20N2O4
纯度 : 99%+
分子量 : 316.35
MDL号 : -
存储条件:

粉末 Sealed in dry,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 250 mg/mL(790.26 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 STING-IN-3 serves as an inhibitor of stimulator of interferon genes (STING) by efficiently inhibiting both hsSTING and mmSTING through covalent targeting of the predicted transmembrane cysteine residue 91, thereby blocking activation-induced palmitoylation of STING [1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.16mL

0.63mL

0.32mL

15.81mL

3.16mL

1.58mL

31.61mL

6.32mL

3.16mL

参考文献

[1]Haag SM, et, al. Targeting STING with covalent small-molecule inhibitors. Nature. 2018 Jul;559(7713):269-273.