产品说明书

7-Ethylcamptothecin

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Chemical Structure| 78287-27-1 同义名 : SN-22
CAS号 : 78287-27-1
货号 : A154645
分子式 : C22H20N2O4
纯度 : 99%
分子量 : 376.405
MDL号 : MFCD06657922
存储条件：

粉末 Inert atmosphere,Room Temperature

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 4 mg/mL(10.63 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 7-Ethylcamptothecin is a camptothecin derivative and an anti-cancer chemical which exhibited a strong activity against various murine tumors through Topo I (topoisomerase) inhibition.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.66mL

0.53mL

0.27mL

13.28mL

2.66mL

1.33mL

26.57mL

5.31mL

2.66mL
参考文献

[1]Yaegashi T, Sawada S, et al. Chemical modification of antitumor alkaloids, 20(S)-camptothecin and 7-ethylcamptothecin: reaction of the E-lactone ring portion with hydrazine hydrate. Chem Pharm Bull (Tokyo). 1993 May;41(5):971-4.

[2]Nagata H, Kaneda N, et al. Action of 7-ethylcamptothecin on tumor cells and its disposition in mice. Cancer Treat Rep. 1987 Apr;71(4):341-8.