产品说明书
(4-NH2)-Exatecan
 |
同义名 : | - |
| CAS号 : | 2495742-21-5 | |
| 货号 : | A1531421 | |
| 分子式 : | C23H21N3O4 | |
| 纯度 : | 95% | |
| 分子量 : | 403.431 | |
| MDL号 : | N/A | |
| 存储条件： |
粉末 Keep in dark place,Inert atmosphere,Room temperature 液体 -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : |
DMSO: 105 mg/mL(260.27 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
|
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | (4-NH2)-Exatecan, a topoisomerase inhibitor and a derivative of Exatecan, is being studied for use in the development of antibody-drug conjugates (ADCs), as outlined in US20200306243A1, compound A[1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
2.48mL 0.50mL 0.25mL |
12.39mL 2.48mL 1.24mL |
24.79mL 4.96mL 2.48mL |
| 参考文献 |
|---|
|
[1]Howard PW, et, al. Compounds and conjugates thereof. US20200306243A1. |