产品说明书
Iproniazid phosphate
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同义名 : | - |
| CAS号 : | 305-33-9 | |
| 货号 : | A152838 | |
| 分子式 : | C9H16N3O5P | |
| 纯度 : | 98% | |
| 分子量 : | 277.214 | |
| MDL号 : | MFCD00012831 | |
| 存储条件： |
粉末 Inert atmosphere,Room Temperature 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 105 mg/mL(378.77 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO H2O: 50 mg/mL(180.37 mM) |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Iproniazid phosphate is a non-selective, irreversible monoamine oxidase (MAO) inhibitor of the hydrazine class. Iproniazid phosphate has antidepressive activity[3]. Isaxonine phosphate induce acute hepatitis which in most cases is reversible after withdrawal of the drug[4]. This amount of octopamine was not significantly increased by either the monoamine oxidase inhibitor iproniazid phosphate (0.1 mM) or the uptake inhibitor desipramine (10 mM) alone, but was by both together. Nominally calcium-free saline containing 20 mM Mg++ significantly decreased octopamine release[5]. Iproniazid phosphate (0.36mM) increased the concentrations of the same acids in osmotically ruptured synaptosomes[6]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
3.61mL 0.72mL 0.36mL |
18.04mL 3.61mL 1.80mL |
36.07mL 7.21mL 3.61mL |
| 参考文献 |
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