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VCP171

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Chemical Structure| 1018830-99-3 同义名 : -
CAS号 : 1018830-99-3
货号 : A1508915
分子式 : C18H12F3NOS
纯度 : 95%
分子量 : 347.354
MDL号 : MFCD34601853
存储条件：

粉末 Keep in dark place,Inert atmosphere,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 VCP171 is a potent positive allosteric modulator (PAM) of adenosine A1 receptor (A1R). VCP171 is effective in reducing excitatory synaptic currents in Lamina II of neuropathic pain model. VCP171 can be used in the study of neuropathic pain[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.88mL

0.58mL

0.29mL

14.39mL

2.88mL

1.44mL

28.79mL

5.76mL

2.88mL
参考文献

[1]Imlach WL, et al. A Positive Allosteric Modulator of the Adenosine A1 Receptor Selectively Inhibits Primary Afferent Synaptic Transmission in a Neuropathic Pain Model. Mol Pharmacol. 2015 Sep;88(3):460-8.