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SR18662

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Chemical Structure| 2505001-62-5 同义名 : -
CAS号 : 2505001-62-5
货号 : A1493794
分子式 : C16H19Cl2N3O4S
纯度 : 95%
分子量 : 420.311
MDL号 : MFCD32693929
存储条件：

粉末 Sealed in dry,Room Temperature

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 120 mg/mL(285.5 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 SR18662, an analog of ML264, exhibits enhanced inhibitory potency against colorectal cancer cells by effectively targeting Krüppel-like factor five (KLF5) with an IC50 value of 4.4 nM. It serves as a valuable tool for colorectal cancer research[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.38mL

0.48mL

0.24mL

11.90mL

2.38mL

1.19mL

23.79mL

4.76mL

2.38mL
参考文献

[1]Julie Kim,et al.The Novel Small-Molecule SR18662 Efficiently Inhibits the Growth of Colorectal Cancer In Vitroand In Vivo.Mol Cancer Ther.2019 Nov;18(11):1973-1984.