产品说明书

DDO-5936

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Chemical Structure| 2355377-13-6 同义名 : -
CAS号 : 2355377-13-6
货号 : A1493606
分子式 : C25H29N5O4S
纯度 : 99%+
分子量 : 495.594
MDL号 : MFCD33398564
存储条件：

粉末 Keep in dark place,Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 12 mg/mL(24.21 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 DDO-5936 is a potent, specific inhibitor of the Hsp90-Cdc37 protein-protein interaction (PPI), useful for research in colorectal cancer [1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.02mL

0.40mL

0.20mL

10.09mL

2.02mL

1.01mL

20.18mL

4.04mL

2.02mL
参考文献

[1]Wang L, et al. Discovery and Optimization of Small Molecules Targeting the Protein-Protein Interaction of Heat Shock Protein 90 (Hsp90) and Cell Division Cycle 37 as Orally Active Inhibitors for the Treatment of Colorectal Cancer. J Med Chem. 2020;63(3):1