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Lanatoside C

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Chemical Structure| 17575-22-3 同义名 : 毛花苷C
CAS号 : 17575-22-3
货号 : A147174
分子式 : C49H76O20
纯度 : 98%
分子量 : 985.116
MDL号 : MFCD00869432
存储条件:

粉末 Sealed in dry,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 50 mg/mL(50.76 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

无水乙醇: 2 mg/mL(2.03 mM),配合低频超声助溶,注意:无水乙醇开封后,易挥发,也会吸收空气中的水分,导致溶解能力下降,请避免使用开封较久的乙醇

动物实验配方:
生物活性
描述 Lanatoside C, a cardiac glycoside, is utilized in the management of congestive heart failure and cardiac arrhythmias. It demonstrates an IC50 of 0.19 μM against dengue virus in HuH-7 cells and is capable of inhibiting all four serotypes of dengue virus, as well as flavivirus Kunjin, alphavirus Chikungunya, Sindbis virus, and human enterovirus 71[1].[2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.02mL

0.20mL

0.10mL

5.08mL

1.02mL

0.51mL

10.15mL

2.03mL

1.02mL

参考文献

[1]Crommentuijn MH, et al. Intracranial AAV-sTRAIL combined with lanatoside C prolongs survival in an orthotopic xenograft mouse model of invasive glioblastoma. Mol Oncol. 2015 Dec 11. pii: S1574-7891(15)00226-4.

[2]Cheung YY, et al. Antiviral activity of lanatoside C against dengue virus infection. Antiviral Res. 2014 Nov;111:93-99.