产品说明书
Chiauranib
 |
同义名 : | Ibcasertib;CS2164 |
| CAS号 : | 1256349-48-0 | |
| 货号 : | A1461903 | |
| 分子式 : | C27H21N3O3 | |
| 纯度 : | 97% | |
| 分子量 : | 435.474 | |
| MDL号 : | MFCD34179475 | |
| 存储条件： |
粉末 Keep in dark place,Inert atmosphere,Room temperature 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 60 mg/mL(137.78 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Chiauranib (CS2164) is a multi-target inhibitor taken orally that acts against tumor angiogenesis. It effectively targets angiogenesis-related kinases (VEGFR1, VEGFR2, VEGFR3, PDGFRα, and c-Kit), the mitosis-related kinase Aurora B, and the chronic inflammation-related kinase CSF-1R, with IC50 values between 1-9 nM, exhibiting potent anticancer effects[1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
2.30mL 0.46mL 0.23mL |
11.48mL 2.30mL 1.15mL |
22.96mL 4.59mL 2.30mL |
| 参考文献 |
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