NH2-C2-NH-Boc

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Chemical Structure| 57260-73-8 同义名 : 单Boc-乙二胺;N-叔丁氧羰基-1,2-乙二胺 ;PROTAC Linker 22
CAS号 : 57260-73-8
货号 : A144595
分子式 : C7H16N2O2
纯度 : 98%
分子量 : 160.214
MDL号 : MFCD00191871
存储条件:

Pure form Keep in dark place,Inert atmosphere,Room temperature

In solvent -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 105 mg/mL(655.37 mM),注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 NH2-C2-NH-Boc, also known as PROTAC Linker 22, is an alkyl chain-based linker essential in the development of PROTAC molecules, emphasizing its role in facilitating the connection between the two functional ligands of PROTACs for targeted protein degradation[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

6.24mL

1.25mL

0.62mL

31.21mL

6.24mL

3.12mL

62.42mL

12.48mL

6.24mL

参考文献

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.