同义名 : | PF-489791 | |
CAS号 : | 853003-48-2 | |
货号 : | A1445357 | |
分子式 : | C20H28N8O4S | |
纯度 : | 99%+ | |
分子量 : | 476.553 | |
MDL号 : | MFCD18782748 | |
存储条件: |
粉末 Sealed in dry,2-8°C 液体 -20°C:3-6个月-80°C:12个月 |
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溶解度 : | - | |
动物实验配方: |
生物活性 | |||
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描述 | PF-00489791 (PF-489791) is a potent inhibitor of phosphodiesterase 5A, with an IC50 of 1.5 nM. It enhances the relaxation of blood vessels in the kidney, which helps to lower blood pressure and improve renal function[1]. |
实验方案 | |||
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1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
2.10mL 0.42mL 0.21mL |
10.49mL 2.10mL 1.05mL |
20.98mL 4.20mL 2.10mL |
参考文献 |
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