产品说明书
L-Menthol
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同义名 : | (-)-薄荷醇;薄荷冰 ;Menthomenthol |
| CAS号 : | 2216-51-5 | |
| 货号 : | A140621 | |
| 分子式 : | C10H20O | |
| 纯度 : | 99+% | |
| 分子量 : | 156.27 | |
| MDL号 : | MFCD00062979 | |
| 存储条件： |
粉末 Sealed in dry,Room Temperature 液体 -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : |
DMSO: 105 mg/mL(671.93 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO H2O: 1.5 mg/mL(9.6 mM)，配合低频超声，并水浴加热至45℃助溶 |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | (-)-Menthol is a principal constituent of peppermint oil and functions by binding to and activating the transient receptor potential melastatin 8 (TRPM8), which is a Ca2+-permeable nonselective cation channel. This interaction leads to an increase in intracellular calcium levels [Ca2+][1]. | ||
| 临床研究 | |||||
|---|---|---|---|---|---|
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
| NCT03564080 | Peripheral Arterial Disease ... 展开 >> Cardiovascular Diseases Intermittent Claudication Coronary Artery Disease 收起 << | Not Applicable | Recruiting | July 2019 | United Kingdom ... 展开 >> Salford Royal NHS Foundation Trust Recruiting Salford, Manchester, United Kingdom, M6 8HD Contact: Edward Caldow, BSc (Hons) 01612958118 e.j.caldow@salford.ac.uk 收起 << |
| NCT02568631 | Autistic Disorder | Not Applicable | Completed | - | France ... 展开 >> Fondation Lenval Nice, France, 06200 Hôpital Pasteur - CHU de Nice Nice, France, 06300 Hôpital psychiatrique de Sainte marie Nice, France, 06300 收起 << |
| NCT02791789 | Autism Spectrum Disorder | Not Applicable | Completed | - | France ... 展开 >> Fondation LENVAL - Hôpitaux Pédiatriques de Nice CHU-LENVAL Nice, France, 06200 收起 << |
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
6.40mL 1.28mL 0.64mL |
32.00mL 6.40mL 3.20mL |
63.99mL 12.80mL 6.40mL |
| 参考文献 |
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