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ABMA

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Chemical Structure| 332108-65-3 同义名 : -
CAS号 : 332108-65-3
货号 : A1365139
分子式 : C18H24BrNO
纯度 : 99%+
分子量 : 350.293
MDL号 : MFCD01826606
存储条件：

粉末 Keep in dark place,Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 120 mg/mL(342.57 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 ABMA is a broad-spectrum inhibitor of intracellular toxins and pathogens. It effectively shields cells from diverse toxins and pathogens, such as viruses, intracellular bacteria, and parasites. ABMA selectively acts within host cell late endosomes, rather than directly targeting the toxin or pathogen itself. It possesses broad-spectrum anti-infection activity [1][2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.85mL

0.57mL

0.29mL

14.27mL

2.85mL

1.43mL

28.55mL

5.71mL

2.85mL
参考文献

[1]Wu Y, et al. ABMA, a small molecule that inhibits intracellular toxins and pathogens by interfering with late endosomal compartments.

[2]Wu Y, et al. DABMA: A Derivative of ABMA with Improved Broad-Spectrum Inhibitory Activity of Toxins and Viruses. ACS Med Chem Lett. 2019 Jul 2;10(8):1140-1147.