产品说明书
Fmoc-Leu-OH
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同义名 : | Fmoc-leucine;N-FMOC-leucine;FMOC-Leu;FMOC-L-Leucine;NSC 334290;NPC 15199 |
| CAS号 : | 35661-60-0 | |
| 货号 : | A132224 | |
| 分子式 : | C21H23NO4 | |
| 纯度 : | 98% | |
| 分子量 : | 353.412 | |
| MDL号 : | MFCD00037133 | |
| 存储条件： |
粉末 Keep in dark place,Sealed in dry,Room Temperature 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 50 mg/mL(141.48 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Fmoc-leucine serves as a selective modulator of PPARγ, triggering its activation with less potency yet comparable maximal effectiveness to that of rosiglitazone. It enhances insulin sensitivity across various mouse models, including normal, diet-induced glucose-intolerant, and diabetic db/db mice. Additionally, Fmoc-leucine is characterized by reduced adipogenic activity[1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
2.83mL 0.57mL 0.28mL |
14.15mL 2.83mL 1.41mL |
28.30mL 5.66mL 2.83mL |
| 参考文献 |
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