生物活性 | |||
---|---|---|---|
描述 | Caroverine HCl is a potent, competitive, and reversible NMDA and AMPA glutamate receptor antagonist. Caroverine HCl is also an antioxidant and calcium blocker with vasodilatory effects. Caroverine HCl can be used in the study of tinnitus in the inner ear[1][2][3].Caroverine HCl inhibited the pressor response of rat hindquarter preparation to potassium chloride (80 mM) and norepinephrine (1 μM) at a concentration of 1 μM for 10 minutes of treatment. Caroverine HCl markedly inhibited contraction induced by isolated rat aorta in response to potassium chloride (40 mM)[3]. |
实验方案 | |||
---|---|---|---|
1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
2.49mL 0.50mL 0.25mL |
12.44mL 2.49mL 1.24mL |
24.88mL 4.98mL 2.49mL |
参考文献 |
---|