产品说明书
Urolithin B
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同义名 : | NSC 94726;3-hydroxy Urolithin |
| CAS号 : | 1139-83-9 | |
| 货号 : | A122397 | |
| 分子式 : | C13H8O3 | |
| 纯度 : | 95% | |
| 分子量 : | 212.201 | |
| MDL号 : | MFCD00034338 | |
| 存储条件： |
粉末 Inert atmosphere,2-8°C 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 250 mg/mL(1178.13 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 靶点 |
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| 描述 | Urolithin B (30-100 μM; 24 h) exhibits anti-inflammatory properties in LPS-stimulated BV2 microglia by modulating pro- and anti-inflammatory molecules. It suppresses NF-κB and AP-1 signaling while upregulating AMPK and downregulating the Akt, JNK, and ERK signaling pathways in LPS-stimulated BV2 cells[1]. Urolithin B (15 μM; 24 h) promotes the growth and differentiation of C2C12 muscle ducts through increased protein synthesis and suppression of the ubiquitin-proteasome pathway[2]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
4.71mL 0.94mL 0.47mL |
23.56mL 4.71mL 2.36mL |
47.13mL 9.43mL 4.71mL |
| 参考文献 |
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