Azelaic acid
产品说明书
 |
同义名 : | 壬二酸 ;Nonanedioic acid;NSC 19493;Anchoic acid;Azelex;Finacea |
| CAS号 : | 123-99-9 | |
| 货号 : | A121847 | |
| 分子式 : | C9H16O4 | |
| 纯度 : | 98% | |
| 分子量 : | 188.221 | |
| MDL号 : | MFCD00004432 | |
| 存储条件： |
Pure form Sealed in dry,Room Temperature In solvent -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : |
DMSO: 105 mg/mL(557.86 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO H2O: 2 mg/mL(10.63 mM)，配合低频超声助溶 |
|
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Azelaic acid, a nine-carbon dicarboxylic acid, is recognized for its antimicrobial activities against Propionibacterium acnes and Staphylococcus epidermidis, which it achieves by inhibiting microbial cellular protein synthesis. Additionally, it exhibits hypopigmentation effects due to its capacity to scavenge free radicals[1].[2]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
5.31mL 1.06mL 0.53mL |
26.56mL 5.31mL 2.66mL |
53.13mL 10.63mL 5.31mL |
| 参考文献 |
|---|
|
[1]Jung HW, et al. Priming in systemic plant immunity. Science. 2009 Apr 3;324(5923):89-91. [4]Harald Gollnick, et al. Azelaic acid 15% gel in the treatment of rosacea. |