生物活性 | |||
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描述 | RIPK1-IN-7 is a potent and selective RIPK1 inhibitor with a Kd value of 4 nM and an IC50 of 11 nM. RIPK1-IN-7 showed excellent anti-metastatic activity in an experimental B16 melanoma lung metastasis model. RIPK1-IN-7 showed potent cytoprotective effects in a TSZ-induced necrotic model of HT29 cells with an EC50 of 2 nM[1]. |
实验方案 | |||
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1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
2.08mL 0.42mL 0.21mL |
10.38mL 2.08mL 1.04mL |
20.77mL 4.15mL 2.08mL |
参考文献 |
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