产品说明书

diABZI STING agonist-1 3HCl

Print
Chemical Structure| 2138299-34-8 同义名 : diABZI STING Agonist-1 (hydrochloride);STING Agonist diABZI;STING Agonist (Compound 3);Diamidobenzimidazole STING Agonist-1;diABZI STING agonist-1 trihydrochloride
CAS号 : 2138299-34-8
货号 : A1164834
分子式 : C42H54Cl3N13O7
纯度 : 99%+
分子量 : 959.32
MDL号 : MFCD31746912
存储条件：

粉末 Inert atmosphere,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 95 mg/mL(99.03 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

H2O: 25 mg/mL(26.06 mM)，配合低频超声助溶
动物实验配方：
生物活性
描述 diABZI STING agonist-1 3HCl is a selective STING agonist with EC50 values of 130 and 186 nM in humans and mice, respectively. diABZI STING agonist-1 3HCl is highly selective for more than 350 kinases at a concentration of 1 μM[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.04mL

0.21mL

0.10mL

5.21mL

1.04mL

0.52mL

10.42mL

2.08mL

1.04mL
参考文献

[1]Ramanjulu JM, et al. Design of amidobenzimidazole STING receptor agonists with systemic activity. Nature. 2018 Nov 7.