生物活性 | |||
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描述 | SC-57461A is a potent, orally active, non-peptide selective inhibitor of LTA4 hydrolase with IC50s of 2.5 nM, 3 nM and 23 nM for recombinant human, mouse and rat LTA4 hydrolase, respectively[1].SC-57461A inhibits ionophore-stimulated LTB4 production in whole blood with IC50s of 49, 166 and 466 nM in human, mouse and rat, respectively[1] . |
实验方案 | |||
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1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
2.75mL 0.55mL 0.27mL |
13.74mL 2.75mL 1.37mL |
27.48mL 5.50mL 2.75mL |
参考文献 |
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