Propylthiouracil

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Chemical Structure| 51-52-5 同义名 : 丙基硫氧嘧啶 ;6-n-Propylthiouracil; 6-Propyl-2-thiouracil; CTK8G2614; 6-(Propyl-d5)-2-thiouracil; Propycil-d5; Propacil-d5; Procasil-d5; Propylthiouracil-d5; NSC 70461; NSC 6498; PTU
CAS号 : 51-52-5
货号 : A115152
分子式 : C7H10N2OS
纯度 : 97%
分子量 : 170.23
MDL号 : MFCD00006041
存储条件：

Pure form Keep in dark place, sealed in dry, room temperature

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(616.8 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Propylthiouracil, known as 6-n-Propylthiouracil and classified as a thioamide antithyroid drug, acts as an inhibitor of thyroperoxidase and DIO1, suitable for use in research related to Graves' disease and hyperthyroidism [1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

5.87mL

1.17mL

0.59mL

29.37mL

5.87mL

2.94mL

58.74mL

11.75mL

5.87mL
参考文献

[1]Lamis Chamas, et al. A Fine Regulation of the Hippocampal Thyroid Signalling Protects Hypothyroid Mice against Glial Cell Activation. Int J Mol Sci. 2022 Oct 8;23(19):11938.

[2]Utsana Puapermpoonsiri, et al. Synergistic effect of phospholipid-based liposomes and propylthiouracil on U-937 cell growth. J Liposome Res. 2005;15(3-4):215-27.