产品说明书

PD-1-IN-17

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Chemical Structure| 1673560-66-1 同义名 : PD1-IN-1
CAS号 : 1673560-66-1
货号 : A1144682
分子式 : C13H22N6O7
纯度 : 99%+
分子量 : 374.35
MDL号 : MFCD30738000
存储条件：

粉末 Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 120 mg/mL(320.56 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

H2O: 100 mg/mL(267.13 mM)
动物实验配方：
生物活性
描述 PD-1-IN-17, extracted from patent WO2015033301A1, is an inhibitor of PD-1 pathway. It demonstrates a significant inhibition of splenocyte proliferation, achieving a 92% reduction at a concentration of 100 nM[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.67mL

0.53mL

0.27mL

13.36mL

2.67mL

1.34mL

26.71mL

5.34mL

2.67mL
参考文献

[1]Pottayil Govindan Nair Sasikumar, et al. 1,3,4-oxadiazole and 1,3,4-thiadiazole derivatives as immunomodulators. WO2015033301A1.