产品说明书

CEP-28122 mesylate hydrochloride

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Chemical Structure| 1354545-57-5 同义名 : -
CAS号 : 1354545-57-5
货号 : A1142474
分子式 : C29H40Cl2N6O6S
纯度 : 99%+
分子量 : 671.635
MDL号 : N/A
存储条件：

粉末 Inert atmosphere,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 CEP-28122 mesylate hydrochloride, a derivative of diaminopyrimidine, is a powerful, selective, and orally available ALK inhibitor that demonstrates an IC50 of 1.9 nM, showcasing antitumor efficacy and favorable pharmacokinetic properties[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.49mL

0.30mL

0.15mL

7.44mL

1.49mL

0.74mL

14.89mL

2.98mL

1.49mL
参考文献

[1]Mangeng Cheng, et al. CEP-28122, a highly potent and selective orally active inhibitor of anaplastic lymphoma kinase with antitumor activity in experimental models of human cancers. Mol Cancer Ther. 2012 Mar;11(3):670-9.