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SMCC

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Chemical Structure| 64987-85-5 同义名 : NSC 344483;Succinimidyl-4-(N-maleimidomethyl cyclohexane)-1-carboxylate;SMCC crosslinker;SMCC, heterobifunctional cross-linker;Succinimidyl 4-(N-maleimidomethyl)cyclohexan-1-carboxylate
CAS号 : 64987-85-5
货号 : A104275
分子式 : C16H18N2O6
纯度 : 97%
分子量 : 334.324
MDL号 : MFCD00009634
存储条件：

粉末 Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 25 mg/mL(74.78 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 SMCC serves as a protein crosslinker. Antigen-specific immune reactions are triggered when spleen cells are bonded with an SMCC-conjugated antigen[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.99mL

0.60mL

0.30mL

14.96mL

2.99mL

1.50mL

29.91mL

5.98mL

2.99mL
参考文献

[1]Guo Y, et al. Potent antigen-specific immune response induced by infusion of spleen cells coupled with succinimidyl-4-(N-maleimidomethyl cyclohexane)-1-carboxylate (SMCC) conjugated antigens. Int Immunopharmacol. 2016 Feb;31:158-68.