There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.
Type
HazMat fee for 500 gram (Estimated)
Excepted Quantity
USD 0.00
Limited Quantity
USD 15-60
Inaccessible (Haz class 6.1), Domestic
USD 80+
Inaccessible (Haz class 6.1), International
USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic
USD 100+
Accessible (Haz class 3, 4, 5 or 8), International
Dihydrocapsiate, belonging to the capsinoid family, functions as an orally active TRPV1 agonist. It can be utilized in research related to metabolic disorders[1].
体外研究
Dihydrocapsiate (at concentrations of 10, 25, and 50 μM, for 48 hours, in human preadipocytes) has no impact on cell viability [1].
Dihydrocapsiate (10 and 20 μM; 8 days; mature adipocytes) significantly reduces the expression of various adipogenic and inflammatory markers (such as SREBP1, FABP4, PLIN1, ADIPOQ and LEPTIN), while boosting the expression of PGC1α (a key regulator of mitochondrial biogenesis) and TBX1 (a marker for "brite" cells) [1].
Dihydrocapsiate (25~200 μM; RAW 264.7 cells) inhibits the release of NO and the generation of intracellular ROS [1].
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