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Vitexicarpin

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Chemical Structure| 479-91-4 同义名 : Casticin
CAS号 : 479-91-4
货号 : A995627
分子式 : C19H18O8
纯度 : 99%+
分子量 : 374.341
MDL号 : MFCD00210481
存储条件：

粉末 Sealed in dry,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(280.49 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Vitexicarpin, a natural product isolated and purified from the fruits of Vitex trifolia L. var. simplicifolia Cham., can significantly reduce vascular inflammation, through inhibition of ROS-NF-κB pathway in vascular endothelial cells, and may become a potential leading drug in the therapy of prostate carcinoma.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.67mL

0.53mL

0.27mL

13.36mL

2.67mL

1.34mL

26.71mL

5.34mL

2.67mL
参考文献

[1]Meng FM, Yang JB, et al. Vitexicarpin induces apoptosis in human prostate carcinoma PC-3 cells through G2/M phase arrest. Asian Pac J Cancer Prev. 2012;13(12):6369-74.

[2]Lee SM, Lee YJ, et al. Vascular protective role of vitexicarpin isolated from Vitex rotundifolia in human umbilical vein endothelial cells. Inflammation. 2012 Apr;35(2):584-93.