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Tigloylgomisin H

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Chemical Structure| 66069-55-4 同义名 : -
CAS号 : 66069-55-4
货号 : A986477
分子式 : C28H36O8
纯度 : 98+%
分子量 : 500.581
MDL号 : -
存储条件:

粉末

液体 -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 Tigloylgomisin H, a natural product isolated and purified from the fruits of Schisandra chinensis, can significantly induce quinone reductase (QR) activity in Hepa1c1c7 mouse hepatocarcinoma cells. It functions as a monofunctional inducer that specifically upregulates phase II enzymes through the Nrf2-ARE pathway, thus represents a potential liver cancer prevention agent.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.00mL

0.40mL

0.20mL

9.99mL

2.00mL

1.00mL

19.98mL

4.00mL

2.00mL

参考文献

[1]Kim YJ, Lee HJ, et al. Simultaneous determination of nine lignans from Schisandra chinensis extract using ultra-performance liquid chromatography with tandem mass spectrometry in rat plasma, urine, and gastrointestinal tract samples: application to the pharmacokinetic study of Schisandra chinensis. J Sep Sci. 2014 Oct;37(20):2851-63.

[2]Zhang WD, Wang Q, et al. Application of ultrahigh-performance liquid chromatography coupled with mass spectrometry for analysis of lignans and quality control of Fructus Schisandrae chinensis. J Sep Sci. 2012 Sep;35(17):2203-9.