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Dihydrosanguinarine

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Chemical Structure| 3606-45-9 同义名 : 13,14-Dihydrosanguinarine;DHSA
CAS号 : 3606-45-9
货号 : A980533
分子式 : C20H15NO4
纯度 : 98%
分子量 : 333.337
MDL号 : MFCD00872066
存储条件:

粉末 Keep in dark place,Sealed in dry,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 4 mg/mL(12 mM),配合低频超声,并水浴加热至45℃助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 Dihydrosanguinarine is a natural compound isolated from the leaves of Macleaya microcarpa with antifungal and anticancer activity.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.00mL

0.60mL

0.30mL

15.00mL

3.00mL

1.50mL

30.00mL

6.00mL

3.00mL

参考文献

[1]Feng G, Zhang J, et al. Inhibitory activity of dihydrosanguinarine and dihydrochelerythrine against phytopathogenic fungi. Nat Prod Res. 2011 Jul;25(11):1082-9.

[2]Vrba J, Dolezel P, et al. Cytotoxic activity of sanguinarine and dihydrosanguinarine in human promyelocytic leukemia HL-60 cells. Toxicol In Vitro. 2009 Jun;23(4):580-8.