Propargyl-PEG1-NH2

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Chemical Structure| 122116-12-5 同义名 : -
CAS号 : 122116-12-5
货号 : A961334
分子式 : C5H9NO
纯度 : 98% T
分子量 : 99.131
MDL号 : MFCD16713446
存储条件:

Pure form Keep in dark place,Inert atmosphere,2-8°C

In solvent -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 105 mg/mL(1059.2 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 Propargyl-PEG1-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTAC[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

10.09mL

2.02mL

1.01mL

50.44mL

10.09mL

5.04mL

100.88mL

20.18mL

10.09mL

参考文献

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.