产品说明书

SB-258585 hydrochloride

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Chemical Structure| 1216468-02-8 同义名 : SB-258585 (hydrochloride)
CAS号 : 1216468-02-8
货号 : A955592
分子式 : C18H23ClIN3O3S
纯度 : 99%+
分子量 : 523.816
MDL号 : MFCD06798382
存储条件:

粉末 Keep in dark place,Inert atmosphere,2-8°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 120 mg/mL(229.09 mM),配合低频超声,并水浴加热至45℃助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 SB-258585 hydrochloride is a high affinity ligand for the 5-HT6 receptor. In human cell lines with recombinant 5-HT6 receptors, SB-258585 hydrochloride binds highly to a single receptor population.SB-258585 can be used to label both recombinant and natural 5-HT6 receptors [1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.91mL

0.38mL

0.19mL

9.55mL

1.91mL

0.95mL

19.09mL

3.82mL

1.91mL

参考文献

[1]Hirst WD, et al. Characterization of [(125)I]-SB-258585 binding to human recombinant and native 5-HT(6) receptors in rat, pig and human brain tissue. Br J Pharmacol. 2000 Aug;130(7):1597-605.