产品说明书
Astemizole
 |
同义名 : | R 43512;NSC 329963;Retolen;Laridal;Paralergin;Histaminos;Hismanal |
| CAS号 : | 68844-77-9 | |
| 货号 : | A928030 | |
| 分子式 : | C28H31FN4O | |
| 纯度 : | 98% | |
| 分子量 : | 458.57 | |
| MDL号 : | MFCD00153919 | |
| 存储条件： |
粉末 Keep in dark place,Sealed in dry,2-8°C 液体 -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : |
DMSO: 120 mg/mL(261.68 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
|
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Astemizole is a synthetic piperidinyl-benzimidazol derivative with antiallergic properties, Astemizole acts as a reversible competitive inhibitor of histamine H1 receptors, with less anticholinergic effects compared to related agents. | ||
| 临床研究 | |||||
|---|---|---|---|---|---|
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
| NCT00699894 | Postoperative Nausea and Vomit... 展开 >>ing 收起 << | Not Applicable | Withdrawn(Logistical difficult... 展开 >>ies running the study) 收起 << | - | United States, New York ... 展开 >> Long Island Jewish Medical Center/Schneider's Children Hospital New Hyde Park, New York, United States, 11040 收起 << |
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
2.18mL 0.44mL 0.22mL |
10.90mL 2.18mL 1.09mL |
21.81mL 4.36mL 2.18mL |
| 参考文献 |
|---|