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Palmitic Acid

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Chemical Structure| 57-10-3 同义名 : 软脂酸 ;Hexadecanoic acid;Cetylic acid;NSC 5030;C16:0 Fatty acid
CAS号 : 57-10-3
货号 : A920864
分子式 : C16H32O2
纯度 : 95%
分子量 : 256.424
MDL号 : MFCD00002747
存储条件:

粉末 Sealed in dry,Room Temperature

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

无水乙醇: 12.5 mg/mL(48.75 mM),配合低频超声助溶,注意:无水乙醇开封后,易挥发,也会吸收空气中的水分,导致溶解能力下降,请避免使用开封较久的乙醇

动物实验配方:
生物活性
描述 Palmitic acid, a natural product isolated and purified from the herbs of Atractylodes macrocephala Koidz., induces down-regulation of APOM expression and anxiety-like behavior in mice while increasing amygdala-based serotonin metabolism. Palmitic acid has a significant impact on proliferation and differentiation of NSCs in vitro and may be useful for elucidating the role of SFAs in regulating NSCs fate in physiological and pathological settings.
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT01826422 Muscular Dystrophy, Duchenne Not Applicable Completed - Mexico ... 展开 >> Unit of Medical Researcha in Nutrition, Pediatric Hospital, IMSS. Mexico city, Mexico, 06720 收起 <<
NCT02410161 Healthy Phase 4 Completed - -
NCT01826422 - Completed - -
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.90mL

0.78mL

0.39mL

19.50mL

3.90mL

1.95mL

39.00mL

7.80mL

3.90mL

参考文献

[1]Moon ML, Joesting JJ, et al. The saturated fatty acid, palmitic acid, induces anxiety-like behavior in mice. Metabolism. 2014 Sep;63(9):1131-40.

[2]Bruhlmann F, Fourage L, et al. Engineering cytochrome P450 BM3 of Bacillus megaterium for terminal oxidation of palmitic acid. J Biotechnol. 2014 Aug 20;184:17-26.