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Goniotriol

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Chemical Structure| 96405-62-8 同义名 : (+)-Goniotriol
CAS号 : 96405-62-8
货号 : A920225
分子式 : C13H14O5
纯度 : 98+%
分子量 : 250.247
MDL号 : N/A
存储条件:

粉末

液体 -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 Goniotriol, a natural product isolated and purified from the herbs of Goniothalamus giganteus, exhibits antiplasmodial activity against Plasmodium falciparum (IC50=2.6 mg/mL)., antimycobacterial activity against Mycobacterium tuberculosis (MIC =100 mg/mL), and cytotoxicity against cancer cells, KB, BC1, NCI-H187, and MCF-7 with IC(50) ranging from 0.4 to 22.7 mg/mL.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.00mL

0.80mL

0.40mL

19.98mL

4.00mL

2.00mL

39.96mL

7.99mL

4.00mL

参考文献

[1]Prasad KR, Gholap SL. Stereoselective total synthesis of bioactive styryllactones (+)-goniofufurone, (+)7-epi-goniofufurone, (+)-goniopypyrone, (+)-goniotriol, (+)-altholactone, and (-)-etharvensin. J Org Chem. 2008 Jan 4;73(1):2-11.

[2]Alkofahi A, Ma WW, et al. Goniotriol from Goniothalamus giganteus. J Nat Prod. 1989 Nov-Dec;52(6):1371-3.