生物活性 | |||
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描述 | HA-100 is recognized as a strong inhibitor of various protein kinases, exhibiting IC50 values of 4 μM for PKG, 8 μM for PKA, 12 μM for PKC, and 240 μM for MLC-kinase. Additionally, HA-100 is employed as an inhibitor of ROCK[1][2]. HA-100 acts as a competitive inhibitor of MLC-kinase and PKC in the presence of ATP, with inhibition constants (Kis) of 61 μM and 6.5 μM, respectively[1]. |
实验方案 | |||
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1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
3.61mL 0.72mL 0.36mL |
18.03mL 3.61mL 1.80mL |
36.06mL 7.21mL 3.61mL |
参考文献 |
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