产品说明书
MSX-122
 |
同义名 : | Q-122 |
| CAS号 : | 897657-95-3 | |
| 货号 : | A912137 | |
| 分子式 : | C16H16N6 | |
| 纯度 : | 98% | |
| 分子量 : | 292.338 | |
| MDL号 : | MFCD18803971 | |
| 存储条件： |
粉末 Keep in dark place,Sealed in dry,2-8°C 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 3 mg/mL(10.26 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | MSX-122, a partial antagonist of CXCR4, impedes the CXCR4/CXCL12 interaction with an IC50 of approximately 10 nM. It does not affect cAMP reduction mediated by the ligands CCR3/CCL5 and CCR5/CCL5. At 100 nM, MSX-122 strongly inhibits the invasion of 78% of MDA-MB-231 cells but does not affect T-tropic HIV infection or show activity in calcium flux assays[1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
3.42mL 0.68mL 0.34mL |
17.10mL 3.42mL 1.71mL |
34.21mL 6.84mL 3.42mL |
| 参考文献 |
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