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Gadolinium chloride

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Chemical Structure| 10138-52-0 同义名 : 氯化钆 ;GdCl3
CAS号 : 10138-52-0
货号 : A907506
分子式 : Cl3Gd
纯度 : 99.95% (REO)
分子量 : 263.609
MDL号 : MFCD00011024
存储条件:

粉末 Inert atmosphere,Room Temperature

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

1M HCl: 100 mg/mL(379.35 mM),配合低频超声,并调节pH至1

动物实验配方:
生物活性
描述 Gadolinium chloride is a specific CaSR agonist.Gadolinium chloride is used in cardiovascular disease research to promote apoptosis in cardiomyocytes, increase ERK1/2 phosphorylation and activate caspase-3. Gadolinium chloride at a concentration of 30 μM for 15 minutes resulted in an increase in Bax expression and caspase-3 activation and a decrease in Bcl-2 expression in H9c2 cells induced by CsA[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.79mL

0.76mL

0.38mL

18.97mL

3.79mL

1.90mL

37.93mL

7.59mL

3.79mL

参考文献

[1]Li X, et al. Calcium Oxalate Induces Renal Injury through Calcium-Sensing Receptor. Oxid Med Cell Longev. 2016;2016:5203801.