产品说明书

Epifriedelanol

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Chemical Structure| 16844-71-6 同义名 : Friedelan-3β-ol;Longan Triterpane A;Friedelan-3beta-ol;β-Friedelinol
CAS号 : 16844-71-6
货号 : A906361
分子式 : C30H52O
纯度 : 99+%
分子量 : 428.733
MDL号 : MFCD04039822
存储条件：

粉末 2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Epifriedelanol, a natural product isolated and purified from the herbs of Vitis trifolia with antitumor activity, exhibits significant inhibition of NF-kappa B, it may be used to treat asthma, and suppresses adriamycin-induced cellular senescence as well as replicative senescence in human fibroblasts (HDFs) and human umbilical vein endothelial cells (HUVECs), suggesting that it can reduce cellular senescence in human primary cells and may be used to develop dietary supplements or cosmetics that modulate tissue aging or aging-associated diseases.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.33mL

0.47mL

0.23mL

11.66mL

2.33mL

1.17mL

23.32mL

4.66mL

2.33mL
参考文献

[1]Yang HH, Son JK, et al. Epifriedelanol from the root bark of Ulmus davidiana inhibits cellular senescence in human primary cells. Planta Med. 2011 Mar;77(5):441-9.

[2]Kundu JK, Rouf AS, et al. Antitumor activity of epifriedelanol from Vitis trifolia. Fitoterapia. 2000 Sep;71(5):577-9.